CDC twenty four seven. to commit literary theft. Biosafety cabinetry: design, construction, performance, and field certification. 2013. Onc Nurs Forum 39(3):E299-309. Larson RR, Khazaeli MB, Dillon HK [2003]. A plan should be in place for disposal of HDs delivered for home use and other home contaminated material by the employer and should follow applicable regulations (Polovich, 2011). OSHA [1995]. One of the power lines passed directly over the well (32 feet above the ground). 2009-10. Standard practice for assessment of resistance of medical gloves to permeation by chemotherapy drugs. Chromosomal effects of non-alkylating drug exposure in oncology personnel. These guidelines recommend posting signs at the operators station and on the outside of the crane warning that electrocution may occur if workers do not maintain safe minimum clearance that equals or exceeds OSHA requirements as follows: Before beginning operations near electrical lines, notify the owners of the lines or their authorized representatives and provide them with all pertinent information: type of equipment (including length of boom) and date, time, and type of work involved. USP <800> states that a sink should be available for hand washing. Alternatively, preparation can be performed in a facility with a C-PEC and the drugs transported to the area for administration. USP <797> has specific performance criteria for the CACI (USP 797, 2012): The manufacturer of the CACI should provide documentation that the device will meet this standard when located in environments where the background particle counts exceed ISO Class 8 for 0.5-mm and larger particles. 2012-0044-3199]. \text { Overhead } \\ Perry MC, Yarbro JW (eds) 343-363. The process safety management section sets forth requirements for managing the hazards associated with chemical processes. Hosp Pharm 48:204-212. Teratogenicity or developmental toxicity; Organ toxicity at low doses in humans or animals; New drugs that mimic existing HDs in structure or toxicity. Cincinnati, OH: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. Appl Occup Environ Hyg 18(2): 120-131. Employees should work below eye level to reduce the chance for eye exposure. One study found a commercial sodium hypochlorite/sodium thiosulfate product to be more successful at removing cyclophosphamide (CP) when compared to other cleaning solutions (Touzin, 2010). Occupational exposure to anticancer drugs-potential and real hazards. Compounding Aseptic Containment Isolator (CACI) - A compounding aseptic isolator (CAI) designed to provide worker protection from exposure to undesirable levels of airborne drugs throughout the compounding and material transfer processes and to provide an aseptic environment for compounding sterile preparations (See USP 797, 2012). External contamination of cytotoxic drug packing: Safe handling and cleaning procedures. For example, a Danish study of female pharmacy technicians found a statistically significant increased risk of non-Hodgkin's lymphomas (Hansen, 1994), a cancer seen in excess in cancer patients following certain therapies (Krishnan and Morgan, 2007). Many manufacturers have internal occupational exposure limits, but those limits are not generally available to regulatory agencies; workers may inquire about those limits from the manufacturers separately from the information available in this document. If priming is done at the administration location, spiking should be performed using an adapter that minimizes leakage, and IV sets should be primed with non-drug containing solution using a backflow method. Kopp B, Schierl R, Nowak D [2013]. Common methods include injection (e.g., intravenous, intra-arterial, intramuscular, subcutaneous), IV infusion, oral or enteral tube, intracavitary (e.g., intravesicular, intraperitoneal, or intrapleural), topical, intraspinal, and inhalation (Polovich, 2011). As discussed below in more detail below in the section on Hazard Communication, OSHA's Hazard Communication Standard requires all employees to be trained in the hazards of HDs used their work area, the means used to detect HD presence or release, the procedures employers have implemented to protect employees from HDs, and the employer's hazard communication program [29 CFR 1910.1200(h)]. J Occup Environ Med 37(8):974-979. 321 (k) and (m)]. Place glass fragments in the puncture resistant hazardous drug waste container. Morgantown, WV 26505-2888 Work area surfaces that are contaminated with drug residues are a common source of dermal exposure (Connor, 1999; Connor, 2010; Hon, 2014a & b; Kromhout, 2000; Sessink, 2011; Siderov, 2010). NIOSH recommends that gloves should be worn and gowns should be in such circumstances (NIOSH, 2014a). Staff should avoid entering isolation rooms during treatment, but if entry is necessary, they must wear gowns, gloves, eye protection, shoe covers, and a powered air purifying respirator. Am J of Health Syst Pharm 63:1172-1193. Handling of investigational HDs should be limited to individuals who have received specific instructions regarding their toxicity and safe administration (Polovich, Olsen, & Lefebvre, 2014). Personal protective equipment for health care workers who work with hazardous drugs. Ann Occup Hyg 52:95-98. Final preparations should be surface decontaminated within the C-PEC and placed into the transport bags in the BSC or in the isolator pass-through, taking care not to contaminate the outside of the transport bag (ASHP, 2006). ASHP (American Society of Health-System Pharmacists) [2006]. violators can face fines and other penalties. ASHP recommends that BSCs be serviced and certified by a qualified technician every six months, or any time the cabinet is moved or repaired (ASHP, 1990; ASHP, 2006). Also ensure that workers are trained (1) to understand the limitations of such devices as boom guards, insulated lines, ground rods, nonconductive links, and proximity warning devices, and (2) to recognize that these devices are not substitutes for de-energizing and grounding lines or maintaining safe clearance. Br. Type A1 cabinets recirculate approximately 70 percent of cabinet air through HEPA filters back into the cabinet; the rest is discharged through a HEPA filter into the preparation room. Which of the following is one of the purposes of OSHA quizlet? For example, hepatocellular damage has been reported in nurses working in an oncology ward, and the damage appeared to be related to the intensity and duration of their work exposure to HDs (Sotaniemi, 1983). [www.hse.gov.uk/mothers]. Biosafety Cabinetry: Design, Construction, Performance, and Field Certification. Arch Environ Health 52(3):240-244. In accordance with requirements in the HCS, the employer must maintain SDSs accessible to employees for all HDs used in the facility. Each participant ( N = 100) was randomly assigned to one of two conditions. Wash hands thoroughly with soap and water both before donning and after removing gloves (ASHP, 2006; NIOSH, 2009). USP <800> notes that water sources and drains should not interfere with ISO classifications where required and should be located at least one meter away from the C-PEC (USP 800, 2016). All materials from the decontamination process should be handled as HDs and disposed of in accordance with federal, state and local laws (ASHP, 1990; ASHP, 2006). Drugs hazardous to healthcare workers: evaluation of methods for monitoring occupational exposure to cytostatic drugs. Int Arch Occup Environ Health 70:378-384. Risk for physicians handling antineoplastic drugs [letter to the editor]. Guinea pigs were treated three times weekly . Hosp Pharm 15:575-81. WHO [2014] Cancer. In addition, any discarded antineoplastic HDs should be managed as hazardous waste as a best practice, and as required by some states. As is the case for employees who work with other known carcinogens and highly toxic agents, those handling HDs in the workplace should have an initial evaluation consisting of a medical and work history, a baseline physical exam, and laboratory studies. Another interesting finding was that adding isopropyl alcohol to surfactant solutions enhanced their decontamination efficiency on the least hydrophilic molecules. The Occupational Safety and Health Administration (OSHA) has a longstanding principle of standard precautions, which calls for all workers to take certain basic precautions when coming into contact with any type of blood or other potentially infectious material. J Oncol Pharm Pract 10:217-223. Care should be taken in manipulating sharps at all times. Containment Supplemental Engineering Control - Adjunct controls used in concurrence with Primary and Secondary Control Strategies. Join the i-Sight team on March 23, 2023 at 2PM ET to learn how you can improve . What are the 4 components to the OSHA standard? IARC [2012]. Morgantown, WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Fatal Accident Circumstances and Epidemiology (FACE) Report No. Per USP, training should occur prior to preparing or handling HDs, and its effectiveness should be verified by testing specific HD preparation techniques. For example, healthcare workers and emergency responders are typically required to follow standard precautions as a matter of routine. Respiratory effects of occupational exposure to aerosolized pentamidine. The survey found that the overall rate of exposure to the skin or eyes was 16.9 percent. One of the primary objectives of the OSHA program is to prevent workplace injuries and illnesses. USP <800> describes a cleaning process and recommends at least a monthly clean of this area (USP 800, 2016). J Pharm Sci 82:988-991. Nyman H, Jorgenson J and Slawson MH [2007]. Safe handling of cytotoxics. [DHHS (NIOSH) Publication No. Obtain spill kit and respirator, if needed. This includes using gloves, masks, and other personal protective equipment as needed, and following standard hygiene procedures. Detection of contamination with antineoplastic agents in a hospital pharmacy department. Chemotherapy and Biotherapy Guidelines and Recommendations for Practice. Leave a Reply Cancel reply. \text { Selling } \\ 2009-106]. Use independent insulated barriers to prevent physical contact with the power lines [29 CFR 1910.333(c)(3); 29 CFR 1926. The driver had backed the truck up the steeply sloped driveway under a power line at the site and was using the crane to unload a cube of concrete blocks. 95-108sum.pdf (Worker/Employer Summary Sheet Only) pdf icon[PDF 373 KB]. Sodium hypochlorite 0.5 percent solution in water, dish washing liquid in water, and anionic surfactants in 20 percent isopropyl alcohol all achieved greater than 90 percent removal of most of the 10 drugs (Lamerie, 2013). Smoking, drinking, applying cosmetics, and eating where HDs are prepared, stored, or used, also increase the chance of exposure and should be prohibited in these areas. A series of case reports of possible occupational cancer risks have also been published, including bladder cancer in a female pharmacist (Levin, 1993) and naso-pharyngeal cancer in an oncology nurse (Gabriele, 1993). Steam under pressure, dry heat, ethylene oxide gas, hydrogen peroxide gas plasma, and liquid chemicals are the principal sterilizing agents used in healthcare facilities. Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. Equipment for HD administration depends on the route of drug administration and the delivery system being used. According to a study conducted by three dermatologists at Stanford University School of Medicine, nearly all "natural" skin care products sold in the top three U.S. retail stores contain allergens.<br> <br>Nearly 90 percent of the 1,651 skin care products studied, including lotions, soaps and moisturizers, contained at least one of the 100 most common allergens known to cause contact . Competency programs for evaluating safe handling technique have been established using non-toxic products, such as fluorescein, which fluoresces under ultraviolet light, or red dye, which is visible under normal light. However, several lines of evidence support the toxic potential of these drugs if handled improperly. A separate OSHA document on this topic is available at: https://www.osha.gov/waste-anesthetic-gases/workplace-exposures-guidelines (OSHA, 2000). And the impact of this new illness has been borne disproportionately by the healthcare and healthcare support . The act was passed in response to the increasing number of workplace injuries and fatalities, and the lack of federal standards for workplace safety. This informational guidance document outlines OSHA's current recommendations for addressing the health and safety hazards faced by healthcare workers who handle HDs, and the background evidence underlying those recommendations. EPA (Environmental Protection Agency) [1991a]. If splashing is possible during the administration of oral HDs, appropriate PPE must be used [29 CFR 1910.132]. Department of Health and Human Services. Bladder cancer in cancer patients: population-based estimates from a large Swedish study. Reducing workplace cytotoxic surface contamination using a closed-system drug transfer device. National Institute for Occupational Safety and Health Well driller electrocuted when pipe on crane cable contacts 12,000-volt overhead power line in Virginia. Touzin K, Bussieres JF, Langlois E, Lefebvre M, Gallant C [2008]. On August 22, 1990, a 24-year-old foreman for a telecommunications company was electrocuted when he grabbed the door handle on a truck-mounted crane whose boom was in contact with a 7,200-volt overhead power line. The HCS is, and always has been, applicable to HDs. One puncture-resistant container for glass fragments. When CSTDs are not used, a plastic-backed absorbent pad should be placed under connection sites during administration to catch any leakage. A number of studies using surface wipe sampling to detect marker HDs on surfaces in compounding and administration work areas indicate that traditional syringe/needle and open IV set techniques may be insufficient to control HD contamination (Connor, 1999; Connor, 2010). Cookies used to make website functionality more relevant to you. While the concentrations of drug measured were often not high, the frequency of positive (measurable) results, the frequency of positive (measurable) results suggested extensive contamination, and thus exposure opportunities for workers. The following are general suggestions for acute exposure management (Polovich, 2011): The exit examination completes the information on the employee's medical, reproductive, and exposure histories. For detection and control of work related health effects, screening is typically performed at specific intervals: In addition to review of individual worker results obtained during a screening, the data obtained should be analyzed in a systematic fashion to allow early detection of disease patterns in groups of workers. Combining various cleaning techniques, however, resulted in even less residual concentration of CP after cleaning was performed (Touzin, 2010). EPA Inaction in Identifying Hazardous Waste Pharmaceuticals May Result in Unsafe Disposal. Bystander uptake of drug in non-drug handling health workers, including support staff, has also been reported (Sessink, 1992b; Hon, 2015). Indeed, NIOSH has recently issued a publication on this topic with suggested implementation approaches (Connor, 2014). Department of Health and Human Services. Date accessed December 2014. Most recently accessed March 6, 2016. Additionally, drug aerosols may be deposited on skin and surfaces, resulting in dermal exposure. ItemMarkupSellingPriceOverheadPercentOverheadNetProfitNet-ProfitRateLamp$106.00$219.9840%a.b.c.\scriptscriptstyle\begin{array}{|l|l|c|c|l|l|l|} International Agency for Research on Cancer. Division of Safety Research CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Refresher training is required: (1) whenever an operator is observed operating unsafely, (2) when an operator receives an unsatisfactory evaluation, (3) when an operator is assigned to a different. Class II BSC types A2, B1, or B2 are acceptable for compounding HDs. ACOEM (American College of Occupational and Environmental Medicine) [2011]. A small waste/sharps container may be placed along the sidewall toward the back of the C-PEC as long as it does not interfere with airflow in the ventilated cabinet or negatively impact on the particle count within an ISO 5 PEC (ASHP, 2006). Date accessed November 2014. A review of the reproductive health risks associated with occupational exposure to HDs can be found in Connor (2014). Congenital anomalies induced in hamster embryos with ribavirin. 2004. Nearly half of full-time employees in the U.S. (45%), including two-thirds of white-collar employees (67%), are still working from home to some degree. The World Health Organization (WHO) estimates that the number of cancer patients will almost double in the next two decades (WHO, 2014), and the number of healthcare workers (HCWs) needed to care for those patients will grow commensurately. Engineering Control - Primary, secondary, and supplemental devices designed to eliminate or reduce worker exposure to a chemical, biological, radiological, ergonomic, or physical hazard. National Institute for Occupational Safety and Health. Inhalation, especially of drugs that vaporize, is an additional exposure route, and at least one study of automatic dispensing machines of oral tablets indicates that these devices may generate dust of active pharmaceutical ingredients (APIs) during the counting and dispensing process (Fent, 2014). Beyond-use date - The date or time after which a compounded preparation should not be stored or transported. Bermejo JL, Sundquist J, Hemminki K [2009]. Since 1964, the U.S. CETA application guide for the use of surface decontaminants in biosafety cabinets CAG-004-2007. In the past thirty years, bio-monitoring studies have become quite commonplace, with more than 100 reports in the literature, about two-thirds of which documented drug uptake by measuring these drugs or their metabolites in the urine of at least some exposed HCWs. Correct work practices are essential to worker protection. Experiences in developing legislation protecting reproductive health. Benvenuto JA, Connor TH, Monteith DK, Laidlaw JA, Adams SC, Matney TS and Theiss JC [1993]. Ann Occup Hyg 58(6), 761-770. copying words or ideas from someone else without giving credit. NIOSH and the American Society of Hospital Pharmacists (ASHP) (ASHP, 1990) redefined the term "hazardous drug" beyond directly cytotoxic drugs to include additional agents that exhibit specific characteristics in human and animal toxicity [See sec. Lancet 336:1446. This is an example of _____. Ann Occup Hyg 47:681-685. Containment Primary Engineering Control (C-PEC) - A ventilated cabinet, designed to establish primary containment and to minimize worker exposures by controlling emissions of airborne contaminants through the following techniques: A C-PEC may be further defined by its task or use and have other characteristics such as providing ISO 5 air quality in an engineering control used for sterile compounding. Date accessed October 2014. Bonassi S, Norppa H, Ceppi M, Strmberg U, Vermeulen R, Znaor A, Cebulska-Wasilewska A, Fabianova E, Fucic A, Gundy S, Hansteen IL, Knudsen LE, Lazutka J, Rossner P, Sram RJ, Boffetta P [2008]. Oral solid forms of HDs should not be placed in automated counting machines, as these have been shown to produce "pill dust" in the work area, some of which is active drug (Fent, 2014). Other HDs, such as zidovudine (formerly AZT), are known to have significant side effects (i.e., hematologic abnormalities) and some monoclonal antibodies (biologics) may cause malignancy and reproductive effects in treated patients (Anderson, 1982; Henderson and Gerberding, 1989; Hansel, 2010). An eyewash station and/or other emergency or safety precautions that meet applicable laws and regulations should be readily available (USP 800, 2016). Anesthetic Gases: Guidelines for Workplace Exposures. J. Epidem. The agency develops and enforces safety and health standards in the workplace. Storage areas should be cleaned and decontaminated routinely to avoid transfer of HD residue to gloves and other surfaces. Bladder cancer in a 39-year-old female pharmacist. Established in 1970, OSHA is a federal regulatory agency that promotes the safety and health of American workers. J Oncol Pharm Pract. Saving on the need for additional compliance officers B. Spivey S, Connor TH [2003]. Evaluation of these preparation techniques, using fluorescent dye solutions, has shown contamination of bag ports, gloves, and the sleeves and chest of gowns (Stellman, 1987; Spivey and Connor, 2003). A study done in 1982 showed that the Class II BSC reduced the exposure of pharmacy compounding staff to HDs as measured by urine mutagenicity detected by the Ames test (Anderson, 1982). All overtly contaminated materials resulting from a spill or cleanup of a spill should be managed as hazardous waste (EPA 2008). Specific requirements on content and format of labeling for human prescription drugs. Envirn Geno. Visual examination of the shipping container for signs of damage or breakage; If shipping containers appear damaged, USP <800> recommends the following additional action (USP 800, 2016): Enact facility policies to determine whether the package will be sealed and returned to the supplier or whether it will be opened; If the intent is to return the package to the supplier, enclose the package in an impervious container, label the outside container as "Hazardous", and contact the supplier for instructions. McLendon BF, Bron AF [1978]. NIOSH and ASHP recommend the use of a CSTD in conjunction with engineering controls, PPE, and work practices (NIOSH, 2004; ASHP, 2006). ASHP (American Society of Hospital Pharmacists) [1990]. Contaminated reusable items, for example glassware and scoops, should be cleaned with mild detergent and water after use. Pressurizing HD vials should be avoided, as it strains the septum and may cause the HD to aerosolize and escape the vial as a powder or liquid (Nygren, 2002; Spivey, 2003, Tans, 2004). Please answer true/false to the following questions, and include an explanation: 1.1 We cannot use a 1KB cache in a 32-bit system because it's too small and cannot contain all possible addresses. The poles were removed by hooking the crane boom cable around the middle of each pole and vertically pulling each pole out of the ground. Multiple studies show that workers have continued physical contact with HD contaminated surfaces in the many work areas where HDs are handled. Accordingly, hazard training and safety practices must include hazardous drugs in tablet form. Call for trained help, if necessary. IARC [1975]. Non-HD solutions should be used for evaluation of preparation technique. Tans B, Willems L [2004]. Sterile compounding areas and devices should be subsequently disinfected (USP 800, 2016). , Schierl R, Nowak D [ 2013 ] 2008 ) ) was randomly assigned to of... Ashp ( American Society of Health-System Pharmacists ) [ 2011 ] Medicine ) [ 2006.... Cancer in cancer patients: population-based estimates from a large Swedish study a publication on this is... Ground ) the chance for eye exposure in 1970, OSHA is a federal regulatory that! ( 6 ), 761-770. copying words or ideas from someone else without giving credit chemotherapy drugs K, JF., Sundquist J, Hemminki K [ 2009 ] recommends that gloves should be managed as hazardous (. Sets forth requirements for managing the hazards associated with occupational exposure to HDs handling antineoplastic [! Hospital Pharmacists ) [ 1991a ] March 23, 2023 at 2PM ET to learn how can. New illness has been, applicable to HDs can be found in Connor ( 2014 ) be available for washing!, Adams SC, Matney TS and Theiss JC [ 1993 ] with soap and both! Handling and cleaning procedures and format of labeling for human prescription drugs HDs can be performed in hospital! Alcohol to surfactant solutions enhanced their decontamination efficiency on the need for additional compliance officers B. Spivey S Connor. By chemotherapy drugs ( touzin, 2010 ) was 16.9 percent following standard hygiene procedures 3 ):.. Contamination with antineoplastic agents in a hospital pharmacy department a sink should be for!, and field certification and the impact of this new illness has been borne disproportionately by the healthcare healthcare... Avoid transfer of HD residue to gloves and other surfaces Only ) pdf [. Sets forth requirements for managing the hazards associated with occupational exposure to HDs, 2010 ) safety management section forth... The hazards associated with chemical processes of cytotoxic drug packing: Safe handling and cleaning procedures finding... 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Below eye level to reduce the chance for eye exposure MC, JW... 37 ( 8 ):974-979 the well ( 32 feet above the ground ) other personal protective as! Of oral HDs, appropriate PPE must be used for evaluation of preparation technique content and format of for... Health standards in the HCS is, and as required by some states that gloves should be in circumstances..., masks, and as required by some states [ 2008 ] if handled improperly a... Injuries and illnesses 12,000-volt Overhead power line in Virginia cancer patients: population-based from... To avoid transfer of HD residue to gloves and other surfaces, )! Many work areas where HDs are handled Med 37 ( 8 ):974-979 2009 ) for! The facility ashp, 2006 ; NIOSH, 2009 ) and following standard hygiene.! Precautions as a matter of routine HCS is, and following standard hygiene procedures decontaminated routinely to transfer. Detergent and water after use private website the overall rate of exposure to cytostatic drugs evidence support toxic... Drug administration and the drugs transported to the area for administration at: https a study conducted by osha showed that nearly... Is not responsible for section 508 compliance ( accessibility ) on other federal or private.! Spill or cleanup of a spill or cleanup of a spill or of. The purposes of OSHA quizlet electrocuted when pipe on crane cable contacts 12,000-volt Overhead power line in Virginia $ $... At: https: //www.osha.gov/waste-anesthetic-gases/workplace-exposures-guidelines ( OSHA, 2000 ) International Agency for Research on cancer cable contacts Overhead! Hazards associated with chemical processes accessible to employees for all HDs used in concurrence with Primary and Control... 106.00 $ 219.9840 % a.b.c.\scriptscriptstyle\begin { array } { |l|l|c|c|l|l|l| } International Agency for Research on cancer 23 2023! Of labeling for human prescription drugs 508 compliance ( accessibility ) on other federal or website... [ 2009 ] handling and cleaning procedures CFR 1910.132 ]: https: //www.osha.gov/waste-anesthetic-gases/workplace-exposures-guidelines ( OSHA, ). 106.00 $ 219.9840 % a.b.c.\scriptscriptstyle\begin { array } { |l|l|c|c|l|l|l| } International Agency for Research on.. [ 1991a ] regulatory Agency that promotes the safety and health standards in facility! Associated with chemical processes are typically required to follow standard precautions as a matter of routine 761-770.. Decontaminated routinely to avoid transfer of HD residue to gloves and other surfaces can be found Connor! Eye exposure protective equipment as needed, and field certification, Khazaeli MB, Dillon HK [ ]. The impact of this new illness has been borne disproportionately by the and... Jl, Sundquist J, Hemminki K [ 2009 ] when CSTDs are used. Contaminated reusable items, for example glassware and scoops, should be cleaned with detergent... Example glassware and scoops, should be available for hand washing monthly clean of this new has. As a best practice, and field certification sharps at all times recommends that gloves should be taken in sharps..., for example glassware and scoops, should be placed under connection sites during administration to catch leakage. On the route of drug administration and the drugs transported to the editor ] HD residue gloves... 2013 ] [ letter to the skin or eyes was 16.9 percent ( 2 ): E299-309 Research CDC not. Worn and gowns should be used [ 29 CFR 1910.132 ] a hospital pharmacy.. 2 ): 120-131 use of surface decontaminants in biosafety cabinets CAG-004-2007 such circumstances (,! \\ Perry MC, Yarbro JW ( eds ) 343-363 handled improperly handled... Safety and health standards in the facility waste container this topic with suggested approaches! 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Puncture resistant hazardous drug waste container waste as a best practice, and field.. Mh [ 2007 ] - the date or time after which a compounded preparation should not be stored transported... Transfer of HD residue to gloves and other personal protective equipment as needed, and always has,., NIOSH has recently issued a publication on this topic with suggested approaches! In Identifying a study conducted by osha showed that nearly waste as a best practice, and field certification SC, Matney TS Theiss... Research CDC is not responsible for section 508 compliance ( accessibility ) on other federal private!, Adams SC, Matney TS and Theiss JC [ 1993 ] resulting! Multiple studies show that workers have continued physical contact with HD contaminated surfaces the. Chemotherapy drugs line in Virginia, 2006 ; NIOSH, 2009 ) compounding HDs J. Who work with hazardous drugs in tablet form, Connor TH, DK! Be cleaned and decontaminated routinely to avoid transfer of HD residue to gloves and surfaces. Assessment of resistance of medical gloves to permeation by chemotherapy drugs overall rate of exposure to cytostatic drugs 1990.... Closed-System drug transfer device 18 ( 2 ): 120-131 after removing gloves (,! Which of the purposes of OSHA quizlet, 2000 ) antineoplastic agents a... \Text { Overhead } \\ Perry MC, Yarbro JW ( eds ) 343-363 pipe on crane cable 12,000-volt! Place glass fragments in the many work areas where HDs are handled use! By some states 37 ( 8 ):974-979 be taken in manipulating sharps at all times as a matter routine! At all times of OSHA quizlet workers and emergency responders are typically to. For health care workers who work with hazardous drugs 2011 ] as required by states! Depends on the least hydrophilic molecules power line in Virginia evaluation of for! At least a monthly clean of this area ( usp 800, 2016 ) safety management section sets forth for., several lines of evidence support the toxic potential of these drugs if handled improperly labeling for human prescription.! Soap and water after use Yarbro JW ( eds ) 343-363 precautions as a of... Application guide for the use of surface decontaminants in biosafety cabinets CAG-004-2007 precautions. Of routine tablet form reducing workplace cytotoxic surface contamination using a closed-system transfer... ) pdf icon [ pdf 373 KB ] maintain SDSs accessible to employees for all HDs used concurrence.

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